Mucoadhesive Microspheres for Controlled Drug Delivery
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چکیده
منابع مشابه
Mucoadhesive Microspheres as a Controlled Drug Delivery System for Gastroretention
Context: Drugs that are easily absorbed from the gastrointestinal tract (GIT) and have a short halflife are eliminated quickly from the blood circulation, require frequent dosing. To avoid this, the oral controlled release (CR) formulations have been developed in an attempt to release the drug slowly into the GIT and maintain a constant drug concentration in the serum for longer period of time....
متن کاملMucoadhesive Microspheres-A Promising Carrier in Drug Delivery: A Review
Corresponding Authors: Sellappan Velmurugan Email: [email protected] Abstract: Carrier technology offers a promising approach for drug delivery system by coupling the drug to a carrier particle such as microspheres,nanoparticles, niosomes, liposomes etc. which modulates the release characteristics of the drug. Mucoadhesion had been a topic of interest in the design of novel drug delive...
متن کاملMucoadhesive Microspheres as carriers in Drug Delivery: a Review
Microspheres constitute an important part of novel drug delivery system by virtue of their small size and efficient carrier capacity. Due to their short residence time, bioadhesive characteristics can be coupled to microspheres to develop mucoadhesive microspheres. Bioadhesion can be defined as the state in which two materials, at least one of which is biological in nature, are held together fo...
متن کاملMicrospheres as a Promising Mucoadhesive Drug Delivery System - Review
International Journal of Pharmaceutical Sciences Review and Research Available online at www.globalresearchonline.net 8 Swapna. S*, Dr. Anna Balaji, Dr. M.S Uma Shankar, A.Vijendar Department of Pharmaceutics, Trinity College of Pharmaceutical Sciences, Karimnagar, Andhra Pradesh, India. Department of Pharmaceutics, Sree Datha Institute of Pharmacy, Ibrahimpatnam, Hyderabad, Andhra Pradesh, Ind...
متن کاملMucoadhesive drug delivery systems
Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to a bioavailability increase and both local and systemic effects. Mucoadhesion is currently explained by six theories: electronic, adsorption, wettability, diff...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2004
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.27.1717